Health care providers

Health care providers

A new tool to aid in the
diagnosis of autism

Clarifi ASD is a highly accurate diagnostic aid that
can help improve early identification of autism

A new tool to aid in the diagnosis of autism

Clarifi ASD is a highly accurate diagnostic aid that
can help improve early identification of autism

Our research papers

Clarifi ASD benefits

Health care providers

Clarifi ASD is a revolutionary epigenetic test, based on peer-reviewed research, that can benefit health care providers and their patients.

Clarifi ASD provides a probability score that informs clinical diagnostics. This should help health care providers make earlier diagnoses, provide more targeted referrals, and facilitate access to intervention services at younger ages.

Clarifi ASD is a biological tool that provides a probability of an autism diagnosis (0-100%). This helps identify children with autism as early as 18 months to expedite access to services.

More clinical application

Diagnostic aid: Clarifi ASD™ is intended to be used with children when there is a suspicion of autism (e.g. positive screening results) as early as 18 months.

HCP collaboration: Test results can facilitate collaboration between primary care and clinicians conducting diagnostic evaluations to expedite early intervention services.

Another tool in the toolbox: Test results provide primary care and specialists biological data to complement behavioral assessments.

Insight for parents: Provides added clarity and prompts next steps toward intervention.

“In too many cases children may not receive a diagnosis until they are 5 years old. Early diagnosis is critical for children with autism, and primary care providers play an important role in that initial process.”


Kristin Sohl, MD, FAAP
Associate Professor, Clinical Child Health – Vice Chair for Quality Improvement, Child Health Department – Advocacy Director, Child Health Department – Director, ECHO Autism
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The Clarifi ASD story

Clarifi ASD was discovered largely by chance. A pediatric resident at SUNY Upstate Medical University, experiencing challenges with the autism diagnostic process, wondered if the epigenetic research he conducted for his PhD training could be applied to autism. So he and his research professor decided to look for a correlation between epigenetic molecules in the saliva (e.g., micro RNA) and autism in children. They hoped to develop a biological test that would decrease the wait time for a final diagnosis and the start of autism specific interventions.

The pilot study, funded by the American Academy of Pediatrics (AAP), provided some unexpected and exciting results: differences in RNA features were found to accurately differentiate children with autism from their peers. This discovery led to a series of larger studies and peer-reviewed publications over the next seven years, culminating in the first ever epigenetic saliva test for autism.

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What’s inside the
Clarifi ASD test kit?

Each saliva test kit includes the following: a collection swab, requisition form, collection instructions, patient instructions, 4 barcode stickers, and a specimen bag.

What’s inside the
Clarifi test kit?

Each saliva test kit Includes the following: a collection swab, requisition form, collection instructions, patient instructions, 4 barcode stickers, and a specimen bag.

Saliva test kit
The kit includes all the necessary components to administer a Clarifi test, including a prepaid UPS shipping label used to return the sample to our lab
Collection instructions
Step-by-step instructions for the health care provider on how to properly administer the Clarifi test and ship the sample to our lab
Patient instructions
Explains how to complete the online questionnaire, and register and pay for the kit
Requisition form
This form is completed and signed by the parent and health care provider after the test is administered Download form
Biospecimen bag
Bag used to store the saliva sample as it gets shipped to our lab
4 barcode stickers
Each kit comes with four unique barcode stickers. The health care provider will place one on the patient instructions, one on the requisition form, and two for office use
Collection swab
This is the swab used to collect the child’s saliva
Each saliva test kit includes the following: a collection swab, requisition form, collection instructions, patient instructions, 4 barcode stickers, and a specimen bag.

What will the results report look like?

Here is the first page of a sample report. Reports are available 3 to 6 weeks after the sample is received and paid for.

Contraindications apply

How Clarifi ASD works

How Clarifi ASD works

Here is an overview of what’s in the Clarifi ASD kit, how to administer the test, shipping the sample and receiving the test results.

Questions? Call us at
866-205-7336