Clarifi autism saliva test
Backed by peer-reviewed research, NIH funded
CLIA-certified, CAP-accredited, HIPAA compliant
Differentiates between autism and other developmental delays
Measures epigenetic molecules in the mouth, including human and microbial RNA
Non-invasive, painless saliva swab performed by your child's physician
Watch this video to learn more about Clarifi and how it will change the way autism spectrum disorder is diagnosed.
Clarifi is an easy to administer, non-invasive, molecular test that accurately identifies children likely to have ASD and should be referred for immediate ASD evaluation. This test provides objective support for earlier diagnosis, when treatment is most efficacious.
Medical researchers from Penn State and SUNY Upstate Medical University have identified certain human and microbial RNAs that can be used to accurately differentiate children on the autism spectrum from both those that are typically developing and those with non-autistic developmental delays. This breakthrough finding was used to develop a sophisticated algorithm that has become the Clarifi autism saliva test.
No. Despite a substantial genetic component, no single gene variant accounts for more than one percent of ASD incidence, so those tests tend to be of limited utility. Clarifi, on the other hand, is an epigenetic test, i.e. it involves modifications to gene expression, rather than changes to the genetic code itself. Epigenetic factors have been implicated in various psychological disorders including depression, schizophrenia, bipolar disorder and autism spectrum disorder.
Clarifi is administered in a doctor's office by taking a quick saliva swab.
Absolutely. The simple, painless saliva swab takes seconds to administer while the parent is in the room.
Our research to date has focused on children in that age range.
The current ASD diagnostic process is typically slow and stressful for parents. This lengthy diagnostic process can lead to delays in accessing intensive interventions that address a child's behavioral, developmental and educational needs. Clinicians need better tools to diagnose ASD at younger ages to expedite treatment services that can improve outcomes and reduce symptoms.
Clarifi should be available to the general public later this year. Once available, Clarifi can be ordered through your pediatrician, family doctor or other healthcare professional who will administer the test.
Once the test has been administered and the sample sent to our lab, results will be sent to your physician 3-6 weeks later.
Clarifi provides an early measurement of epigenetic differences associated with ASD and should be used in combination with developmental and behavioral assessments. There is currently no definitive diagnostic test for ASD. Clarifi results should be interpreted by the ordering physician in the context of the child's personal medical history. Clarifi may expedite the diagnostic process and provide clinicians and parents with more confidence in the diagnosis.
We hope you got a chance to stop by our booth at the American Academy of Pediatrics Meeting in Orlando. If you missed us, we'd still love to hear from you.Contact us